This policy paper seeks to identify and present opportunities and challenges non-state actors (NSA) have when seeking to enhance the enforcement of legislation on bribery in transnational business transactions. It does so by first defining the terms ‘transnational business transactions’, ‘NSA’ and the group of actors nestled within it. The paper then presents a brief overview of the efforts to implement a transnational legal framework to combat bribery in transnational business transactions since the 1970s and how NSAs have sought to support, expand and strengthen this international framework, leading to the anti-corruption drive of the late-1990s. The paper additionally establishes a non-exhaustive list of activities NSAs undertake in the field of preventing and combating corruption. The conclusion presents opportunities and challenges which NSAs may encounter in the prevention and combating of transnational corruption.